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Now showing items 11-20 of 36
Sld5, A Subunit of the Heterotetrameric GINS Complex is Necessary for Normal Cell Cycle Progression and Genomic Stability
(East Carolina University, 2010)
Sld5 is one component of the GINS heterotetrameric complex essential to DNA replication. Specifically, GINS is known for its integral role during the G1 to S phase transition in the cell cycle. The GINS complex is comprised ...
EXPLORING THE BYSTANDER EFFECT FOLLOWING VERY LOW DOSE RADIATION
(East Carolina University, 2010)
Bystander effects are defined as the phenomenon in which unirradiated cells respond biologically when their neighbors are irradiated. The exact mechanisms of these cellular responses are still not known, especially in ...
Predator Out of Place : The Differential Impacts of Native and Non-native Crayfish on Bufo Tadpoles
(East Carolina University, 2010)
Predators have been shown to alter important fitness components (larval period, mass at metamorphosis, and overall survivorship) of larval anurans. Uncommonly studied predators of tadpoles include crayfish. Both native and ...
DEHP Impairs Zebrafish Reproduction by Affecting Critical Factors in Oogenesis
(East Carolina University, 2010-04-15)
Public concerns on phthalates distributions in the environment have been increasing since they can cause liver cancer, structural abnormalities and reduce sperm counts in male reproductive system. However, few data are ...
Effects of 5-fluorouracil Drug Treatment on the Expression Profile of MicroRNAs in MCF7 Breast Cancer Cells
(East Carolina University, 2010)
Breast cancer is one of the leading causes of deaths in women worldwide. 5-flourouracil (5-FU) is a classic chemotherapeutic drug that has been widely used in the treatment of breast cancer patients. In this study, using ...
Coevolutionary analysis of Appalachian Xystodesmid millipedes and their symbiotic Mesostigmatid mites
(East Carolina University, 2010)
Mites (Acari) form symbiotic relationships with many animal taxa including fish, amphibians, reptiles, birds, mammals, mollusks, and arthropods. They are frequently found living on millipedes, and it has often been ...
Tumor Growth Induces Oxidative Clustered DNA Lesions Damage in Distant Mouse Tissue in vivo
(East Carolina University, 2010)
Our goal was to ascertain if DNA damage induced by oxidative stress is capable of being exploited as a precancerous or cancer biomarker. The specific DNA damage that we assessed was oxidatively induced non-DSB clustered ...
EFFECTS OF A REVERSE OSMOSIS-WATER TREATMENT PLANT BRINY CONCENTRATE DISCHARGED INTO AN ESTUARY.
(East Carolina University, 2010)
Reverse Osmosis Water Treatment Plants (RO-WTPs) create potable water and a briny concentrate that must be disposed; often it is discharged into nearby surface waters. Currently, there is no published research to examine ...
Does history matter? : An experimental assessment of whether dragonfly colonization history affects insect biodiversity within ephemeral ponds
(East Carolina University, 2010)
Current interactions among species could have an important role in controlling biodiversity. Some studies, however, have shown that the particular time a species arrives at a site during the process of community assembly ...
Phylogenetics and Systematics of the Millipede genus Brachycybe Wood, 1864 (Platydesmida: Andrognathidae)
(East Carolina University, 2010)
The genus Brachycybe Wood, 1864 (Platydesmida: Andrognathidae) belongs to an ancient millipede lineage that has persisted since the Miocene. The group displays a Holarctic distribution with species in the eastern Nearctic, ...