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TOXICITY OF METAL OXIDE NANOPARTICLES TO CAENORHABDITIS ELEGANS
(East Carolina University, 2012)
The increase in manufacturing and use of nanoparticles is expected to elevate levels of exposure to humans and other organisms. Presently, there is little understanding of the potential toxic effects of nanoparticle exposure. ...
Cryptic Seed Heteromorphism in Packera tomentosa (Asteraceae) : Differences in Seed Mass Characteristics and Germination
(East Carolina University, 2012)
Germination requirements of seeds can dictate when and where plant offspring establish. Microsites available for germination vary spatially and temporally in factors such as temperature and moisture; thus, the production ...
Local and Regional Aspects of Habitat Quality Jointly Affect the Biodiversity of Ephemeral Ponds
(East Carolina University, 2012)
The biodiversity of local communities is likely affected by both local habitat quality and by the quality of the landscape surrounding the locality. In pond environments, habitat quality may be affected by the kind of leaf ...
VALIDATION OF CANDIDATE GENES IN RESPONSE TO VERSICAN MANIPULATION IN DEVELOPING SYNOVIAL JOINTS
(East Carolina University, 2012)
Little is understood about the complex process of synovial joint formation in early limb development. It has been shown that versican is highly expressed in the extracellular matrix of these joints (Snow et al., 2005; ...
Drosophila Psf2 Has a Role In Chromosome Condensation
(East Carolina University, 2012)
The condensation state of chromosomes is a critical parameter in multiple processes within the cell. Failures in the maintenance of appropriate condensation states may lead to genomic instability, mis-expression of genes, ...
The effects of environmental nickel toxicity upon survival, growth, reproduction, fecundity, and lifespan of nematodes Caenorhabditis elegans, Pristionchus pacificus, and Caenorhabditis briggsae
(East Carolina University, 2012)
Nickel (II) is a common component of many natural products and man-made devices. Due to its frequent use in everyday life, relatively large amounts of nickel are being released into the environment. Nickel, however, is a ...
Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)
Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ...
Conspicuous female ornamentation and male mate preference of Threespine Sticklebacks (Gasterosteus aculeatus)
(East Carolina University, 2012)
Sexual selection drives the evolution of exaggerated male ornaments (traits showing little function outside social interactions) in many animal species. Female ornamentation is now acknowledged also to be common but is ...
Lateral Gene Transfer between Bacteria and Trichoderma reesei
(East Carolina University, 2012)
Lateral gene transfer (LGT) has played an important role in shaping the `tree of life'. It has promoted evolution by generating gene redundancies, which allow for more freedom in terms of allowed mutations in a genome, ...
Analysis of Complex DNA Damage Associated with Tumor Growth
(East Carolina University, 2012)
The innate response of a fully functioning immune system's ability to recognize and react to the growth of a tumor by releasing reactive oxygen species (ROS) may lead to chronic inflammation in many cases. This chronic ...