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Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...
Drosophila Ctf4 is essential for genome stability and normal cell cycle progression
(East Carolina University, 2010)
Proper DNA replication and well-timed cell cycle progression are vital to the normal functioning of a cell. Precise coordination between these mechanisms' constituent proteins ensures their processivity while safeguarding ...
Footprints in the sand: independent reduction of subdigital lamellae in the Namib–Kalahari burrowing geckos
(East Carolina University, 2006-04-07)
Many desert organisms exhibit convergence, and certain physical factors such as windblown sands have generated remarkably similar ecomorphs across divergent lineages. The burrowing geckos Colopus, Chondrodactylus and ...
Molecular phylogenetic evidence for a mimetic radiation in Peruvian poison frogs supports a Müllerian mimicry hypothesis.
(East Carolina University, 2001-12-07)
Examples of Müllerian mimicry, in which resemblance between unpalatable species confers mutual benefit, are rare in vertebrates. Strong comparative evidence for mimicry is found when the colour and pattern of a single ...
USE OF GENETIC TECHNIQUES TO IDENTIFY THE DIET OF COWNOSE RAYS, RHINOPTERA BONASUS, IN NORTH CAROLINA AND VIRGINIA : AN ANALYSIS OF SHELLFISH PREY ITEMS
(East Carolina University, 2013)
Cownose rays, Rhinoptera bonasus, are considered voracious predators on mollusks and have been implicated in the consumption of commercially important species of shellfish on the East Coast. Digestive tracts of the 32 ...
Molecular Epidemiology of MRSA Among Patients and Employees in a Surgical Intensive Care Unit
(East Carolina University, 2011)
Methicillin-resistant Staphylococcus aureus (MRSA) is a pervasive drug resistant human pathogen and has become widespread in hospitals around the world. MRSA infections cause approximately 19,000 deaths among hospitalized ...
Simultaneous Positive and Purifying Selection on Overlapping Reading Frames of the tat and vpr Genes of Simian Immunodeficiency Virus
(East Carolina University, 2001-09)
Tat-specific cytotoxic T cells have previously been shown to exert positive Darwinian selection favoring amino acid replacements of an epitope of simian immunodeficiency virus (SIV). The region of the tat gene encoding ...
Development of Fed and Starved Striped Bass (Morone saxatilis) Larvae from the Roanoke River, North Carolina
(East Carolina University, 1986-07)
Fed and unfed striped bass larvae were reared in a laboratory using ambient Roanoke River water to determine differences in growth and development. These differences were used to histologically determine the nutritional ...
Are Marine Migrations of Striped Bass Genetically Pre-determined? : An investigation of Albemarle Sound-Roanoke River Striped Bass Migratory Patterns
(East Carolina University, 2010)
Striped bass, Morone saxatilis, is one of the most thoroughly studied anadromous fish species in the United States, with records governing the management of the species dating back to the late 1600s. However, management ...
THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
(East Carolina University, 2010)
Tumor vascularization is an important control point in cancer progression and its inhibition is a promising approach to cancer therapy. Stromal-derived factor-1 alpha (SDF-1 alpha or CXCL12) is a chemoattractant for ...