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Simultaneous Positive and Purifying Selection on Overlapping Reading Frames of the tat and vpr Genes of Simian Immunodeficiency Virus
(East Carolina University, 2001-09)
Tat-specific cytotoxic T cells have previously been shown to exert positive Darwinian selection favoring amino acid replacements of an epitope of simian immunodeficiency virus (SIV). The region of the tat gene encoding ...
Ancient Genome Duplications Did Not Structure the Human Hox-Bearing Chromosomes
(East Carolina University, 2001-05)
The fact that there are four homeobox (Hox) clusters in most vertebrates but only one in invertebrates is often cited as evidence for the hypothesis that two rounds of genome duplication by polyploidization occurred early ...
Comparison of the exoS Gene and Protein Expression in Soil and Clinical Isolates of Pseudomonas aeruginosa
(East Carolina University, 2001-04)
Exoenzyme S (ExoS) is translocated into eukaryotic cells by the type III secretory process and has been hypothesized to function in conjunction with other virulence factors in the pathogenesis of Pseudomonas aeruginosa. ...