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Simultaneous Positive and Purifying Selection on Overlapping Reading Frames of the tat and vpr Genes of Simian Immunodeficiency Virus
(East Carolina University, 2001-09)
Tat-specific cytotoxic T cells have previously been shown to exert positive Darwinian selection favoring amino acid replacements of an epitope of simian immunodeficiency virus (SIV). The region of the tat gene encoding ...