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Characterizing Interactions of Thioflavin-T with Native Proteins Especially Bovine Serum Albumin
(East Carolina University, 2017-05-03)
Thioflavin T is a fluorescent probe used to monitor formation of cross [beta]-sheet rich amyloid fibrils. Involvement of the amyloid fibrils is implicated in more than 50 human diseases, such as Alzheimer's, Parkinson's ...
How do modified nanoclays adversely affect aquatic species relative to natural nanoclay?
(East Carolina University, 2017-07-17)
Nanoclays represent a large class of modified nanomaterials (NMs) (i.e. nanoscale particles from 1 to 100 nm) that has received great attention from the scientific and industrial communities. This material has been widely ...
Impact of Vessel Noise on Oyster Toadfish (Opsanus tau) Behavior and Implications for Underwater Noise Management
(East Carolina University, 2017-05-03)
Underwater noise and its impacts on marine life are growing management concerns. This dissertation considers both the ecological and social concerns of underwater noise, using the oyster toadfish (Opsanus tau) as a model ...
Characterization of the Bone Marrow Microenvironment During the Development of Triple Negative Breast Cancer Metastases
(East Carolina University, 2017-05-05)
Triple negative breast cancer (TNBC) is a subtype that lacks expression of progesterone and estrogen receptors, and does not over-express human epidermal growth factor receptor 2 (HER2). TNBC is not responsive to standard ...
TGF-β1-directed Smad3 stimulates proliferation and alters morphology of rat primary vascular smooth muscle cells
(East Carolina University, 2017-05-05)
With cardiovascular disease (CVD) being the leading cause of morbidity and death in the United States and worldwide (2, 28), studying the mechanisms of these pathologies is imperative. Recent studies have shown that a ...
Do female Eastern Bluebirds trade-off egg size with clutch size?
(East Carolina University, 2017-05-09)
Egg size and clutch size are traits that show a fundamental trade-off in life history theory. Producing a larger number of offspring can come at the cost of being able to invest in those offspring. The degree of maternal ...
The Fundulus diaphanus Species Complex: A Case Study of Convergent Evolution?
(East Carolina University, 2017-05-09)
The Fundulus diaphanus (banded killifish) species complex of Eastern North Carolina streams and Carolina bays provides a possible case study of convergent evolution with important conservation implications. It was originally ...
Microsatellite analysis of brook trout, Salvelinus fontinalis, in western Pennsylvania
(East Carolina University, 2017-05-05)
In western Pennsylvania, the brook trout, Salvelinus fontinalis, has dramatically declined in population due to the environmental stressors of mining, logging, water withdrawal, and acid deposition. Brook trout are game ...
The Effects of Benzoic Acid in C. elegans: Germ Cell Apoptosis
(East Carolina University, 2017-05-05)
Benzoic acid is widely consumed by humans everyday through means of fruit juices, soft drinks, pickles, salad dressings and more. However, the health impact of long-term benzoic acid exposure remains largely unknown. This ...
Social Enterprises: The Intersection of Business and Humanity
(East Carolina University, 2017-05-03)
Consumers today are becoming more conscience of the businesses they support. Whether it is buying groceries, clothing, or furniture, consumers are now turning to the environmentally friendly and socially responsible ...