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Deep Sequencing Reveals Transcriptome Re-Programming of Cells to the Elicitation with Methyl Jasmonate
(2013)
Background
Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ...
Connecting Mutations of the RNA Polymerase II C-Terminal Domain to Complex Phenotypic Changes Using Combined Gene Expression and Network Analyses
(2010)
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is essential for mRNA synthesis and processing, through coordination of an astounding array of protein-protein interactions. ...
Selection of Reliable Reference Genes in for Analysis of Nanotoxicity
(2012)
Despite rapid development and application of a wide range of manufactured metal oxide nanoparticles (NPs), the understanding of potential risks of using NPs is less completed, especially at the molecular level. The nematode ...
Characterizing the vegetative phenotype of fzt maize mutant
(East Carolina University, 2012)
microRNAs are short, non-coding RNA strands that regulate gene expression post-transcriptionally in all multicellular organisms. miRNAs begin as a hairpin in the nucleus. The primary miRNA (pri-miRNA) and preliminary ...
SPATIAL EXPRESSION OF MATRIX AND MATRIX RECEPTOR PROTEINS IN THE DEVELOPING SYNOVIAL JOINT
(East Carolina University, 2013)
Little is understood about the complex spatial and temporal molecular interactions necessary to form a fully functional synovial joint. Understanding molecular pathways and signaling within the developing joint continues ...
Genome-Wide Functional Analysis of the Cotton Transcriptome by Creating an Integrated EST Database
(2011)
A total of 28,432 unique contigs (25,371 in consensus contigs and 3,061 as singletons) were assembled from all 268,786 cotton ESTs currently available. Several in silico approaches [comparative genomics, Blast, Gene Ontology ...
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...
The effects of sodium butyrate on Hox gene expression in a human colorectal adenocarcinoma cell line, HT29.
(East Carolina University, 2013)
Hox genes are a subgroup of the large family of homeobox containing genes, known to pattern anterior/posterior and proximal/distal axes during embryonic development. More recently Hox gene research has focused on the role ...
Hox Gene Expression During Oreochromis niloticus Pharyngeal Arch Development : Discovering the Hox Code
(East Carolina University, 2010)
Hox genes encode transcription factors and have been extensively studied by evolutionary and developmental biologists. Hox genes are responsible for determining specific regional identities along the anterior-posterior and ...
A Functional Analysis of microRNAs in Nicotiana tabacum
(East Carolina University, 2012)
MicroRNAs (miRNAs) are a newly discovered class of endogenous post-transcriptional gene regulators that are typically 20-22 nucleotides in length that do not code for proteins. MiRNAs regulate gene expression by either ...