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Interaction and Functional Analysis of Drosophila Mcm10
(East Carolina University, 2010)
In eukaryotic cells, DNA replication and the subsequent packaging of DNA into specific chromatin states are essential processes for the transmission of genetic material and genomic stability which may be linked by interactions ...
Characterization of the GINS subunit psf1 in Drosophila Melanogaster
(East Carolina University, 2010)
GINS (Go Ichi Ni San; 5,1,2,3 in Japanese) is a heterotetrameric protein complex known to be essential for the establishment of DNA replication forks and the progression of the replisome. The GINS complex is known to be ...
Drosophila Ctf4 is essential for genome stability and normal cell cycle progression
(East Carolina University, 2010)
Proper DNA replication and well-timed cell cycle progression are vital to the normal functioning of a cell. Precise coordination between these mechanisms' constituent proteins ensures their processivity while safeguarding ...