Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review
Author
Ibrahim, Badr M.; Abdel-Rahman, Abdel A.
Abstract
Cannabinoids elicit complex hemodynamic responses in experimental animals that involve both peripheral and central sites. Centrally administered cannabinoids have been shown to predominantly cause pressor response. However, very little is known about the mechanism of the cannabinoid receptor 1 (CB1R)-centrally evoked pressor response. In this review, we provided an overview of the contemporary knowledge regarding the cannabinoids centrally elicited cardiovascular responses and the possible underlying signaling mechanisms. The current review focuses on the rostral ventrolateral medulla (RVLM) as the primary brainstem nucleus implicated in CB1R-evoked pressor response.
Subject
Date
2013-04
Citation:
APA:
Ibrahim, Badr M., & Abdel-Rahman, Abdel A.. (April 2013).
Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review.
Journal of Advanced Research,
5(2),
137-
145. Retrieved from
http://hdl.handle.net/10342/5767
MLA:
Ibrahim, Badr M., and Abdel-Rahman, Abdel A..
"Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review". Journal of Advanced Research.
5:2. (137-145),
April 2013.
December 11, 2023.
http://hdl.handle.net/10342/5767.
Chicago:
Ibrahim, Badr M. and Abdel-Rahman, Abdel A.,
"Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review," Journal of Advanced Research 5, no.
2 (April 2013),
http://hdl.handle.net/10342/5767 (accessed
December 11, 2023).
AMA:
Ibrahim, Badr M., Abdel-Rahman, Abdel A..
Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review. Journal of Advanced Research.
April 2013;
5(2):
137-145.
http://hdl.handle.net/10342/5767. Accessed
December 11, 2023.
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