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    Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review

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    Author
    Ibrahim, Badr M.; Abdel-Rahman, Abdel A.
    Abstract
    Cannabinoids elicit complex hemodynamic responses in experimental animals that involve both peripheral and central sites. Centrally administered cannabinoids have been shown to predominantly cause pressor response. However, very little is known about the mechanism of the cannabinoid receptor 1 (CB1R)-centrally evoked pressor response. In this review, we provided an overview of the contemporary knowledge regarding the cannabinoids centrally elicited cardiovascular responses and the possible underlying signaling mechanisms. The current review focuses on the rostral ventrolateral medulla (RVLM) as the primary brainstem nucleus implicated in CB1R-evoked pressor response.
    URI
    http://hdl.handle.net/10342/5767
    Subject
     Cannabinoids; ERK1/2; nNOS; PI3K; Cardiovascular; RVLM 
    Date
    2013-04
    Citation:
    APA:
    Ibrahim, Badr M., & Abdel-Rahman, Abdel A.. (April 2013). Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review. Journal of Advanced Research, (5:2), p.137-145. Retrieved from http://hdl.handle.net/10342/5767

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    MLA:
    Ibrahim, Badr M., and Abdel-Rahman, Abdel A.. "Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review". Journal of Advanced Research. 5:2. (137-145.), April 2013. March 03, 2021. http://hdl.handle.net/10342/5767.
    Chicago:
    Ibrahim, Badr M. and Abdel-Rahman, Abdel A., "Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review," Journal of Advanced Research 5, no. 2 (April 2013), http://hdl.handle.net/10342/5767 (accessed March 03, 2021).
    AMA:
    Ibrahim, Badr M., Abdel-Rahman, Abdel A.. Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review. Journal of Advanced Research. April 2013; 5(2) 137-145. http://hdl.handle.net/10342/5767. Accessed March 03, 2021.
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