Author | Mitchell, James E. | |
Author | King, Wendy C. | |
Author | Chen, Jia-Yuh | |
Author | Devlin, Michael J. | |
Author | Flum, David | |
Author | Garcia, Luis | |
Author | Pender, John R. | |
Author | Kalarchian, Melissa A. | |
Author | Khandelwal, Saurabh | |
Author | Marcus, Marsha D. | |
Author | Schrope, Beth | |
Author | Strain, Gladys | |
Author | Wolfe, Bruce | |
Author | Yanovski, Susan | |
Date Accessioned | 2016-07-28T18:14:30Z | |
Date Available | 2016-07-28T18:14:30Z | |
Date of Issue | 2014-05 | |
Identifier (Citation) | Obesity (Silver Spring, Md.); 22:8 p. 1799-1806 | en_US |
ISSN | 1930-7381 | |
Identifier (URI) | http://hdl.handle.net/10342/5854 | |
Description | Objective
To examine changes in depressive symptoms and treatment in the first three years following bariatric surgery.
Design and Methods
The Longitudinal Assessment of Bariatric Surgery-2 is an observational cohort study of adults (n=2,458) who underwent a bariatric surgical procedure at one of ten US hospitals between 2006–9. This study includes 2,148 participants who completed the Beck Depression Inventory (BDI) at baseline and ≥ one follow-up visit in years 1–3.
Results
At baseline, 40.4% self-reported treatment for depression. At least mild depressive symptoms (BDI score≥10) were reported by 28.3%; moderate (BDI score 19–29) and severe (BDI score ≥30) symptoms were uncommon (4.2% and 0.5%, respectively). Mild-to-severe depressive symptoms independently increased the odds (OR=1.75; p=.03) of a major adverse event within 30 days of surgery. Compared with baseline, symptom severity was significantly lower at all follow-up time points (e.g., mild-to-severe symptomatology was 8.9%, 6 months; 8.4%, 1yr; 12.2%, 2yrs; 15.6%, 3yrs; ps<.001), but increased between 1 and 3 years postoperatively (p<.01). Change in depressive symptoms was significantly related to change in body mass index (r=.42; p<0001).
Conclusion
Bariatric surgery has a positive impact on depressive features. However, data suggest some deterioration in improvement after the first postoperative year. | en_US |
Related URI | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115026/ | en_US |
Subject | Roux-en-Y gastric bypass | en_US |
Subject | laparoscopic adjustable gastric band | en_US |
Subject | severe obesity | en_US |
Subject | weight loss | en_US |
Subject | treatment | en_US |
Subject | depression | en_US |
Subject | antidepressant medication | en_US |
Title | Course of Depressive Symptoms and Treatment in the Longitudinal Assessment of Bariatric Surgery (LABS-2) Study | en_US |
Type | Article | en_US |
Identifier (PMID) | pmc4115026 | en_US |
Identifier (DOI) | 10.1002/oby.20738 | |
Journal Name | Obesity (Silver Spring, Md.) | en_US |
Journal Volume | 22 | en_US |
Journal Issue | 8 | en_US |
Article Pages | 1799-1806 | en_US |