Browsing Other Campus Research by Author "Akula, Shaw M."
-
KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain
Hussein, Hosni; Walker, Lia; Akula, Shaw M. (2016-02-24)Background: Kaposi’s sarcoma-associated herpesvirus (KSHV) glycoprotein B (gB) is not only expressed on the envelope of mature virions but also on the surfaces of cells undergoing lytic replication. Among herpesviruses, KSHV ... -
miRNA-36 inhibits KSHV, EBV, HSV-2 infection of cells via stifling expression of interferon induced transmembrane protein 1 (IFITM1)
Hussein, Hosni A. M.; Akula, Shaw M. (2017-12-21)Kaposi’s sarcoma-associated herpesvirus (KSHV) is etiologically associated with all forms of Kaposi’s sarcoma worldwide. Little is currently known about the role of microRNAs (miRNAs) in KSHV entry. We recently demonstrated ... -
Resveratrol inhibits KSHV reactivation by lowering the levels of cellular Egr-1
Dyson, Ossie F.; Walker, Lia R.; Whitehouse, Adrian; Cook, Paul P.; Akula, Shaw M. (2012-03-12)In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma-associated herpesvirus (KSHV) primarily exists in a latent state, while ... -
Subcellular fractionation method to study endosomal trafficking of Kaposis sarcoma-associated herpesvirus
Walker, Lia R.; Akula, Shaw M.; Hussein, Hosni A. M. (2016)Background: Virus entry involves multiple steps and is a highly orchestrated process on which successful infection collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles via ...