Browsing Other Campus Research by Author "Hall, M. Kristen"
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Glycan Structures Contain Information for the Spatial Arrangement of Glycoproteins in the Plasma Membrane
Hall, M. Kristen; Weidner, Douglas A.; Chen, Jian ming; Bernetski, Christopher J.; Schwalbe, Ruth A. (2013-09-06)Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information ... -
Lack of complex type N-glycans lessens aberrant neuronal properties
Hall, M. Kristen; Weidner, Douglas A.; Whitman, Austin A.; Schwalbe, Ruth A. (2018-06)Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-Nasparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of ... -
Predominant Expression of Hybrid N-Glycans Has Distinct Cellular Roles Relative to Complex and Oligomannose N-Glycans
Hall, M. Kristen; Weidner, Douglas A.; Zhu, Young; Dayal, Sahil; Whitman, Austin A.; Schwalbe, Ruth (2016-06)Glycosylation modulates growth, maintenance, and stress signaling processes. Consequently, altered N-glycosylation is associated with reduced fitness and disease. Therefore, expanding our understanding of N-glycans in ...