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  • Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells 

    Opyrchal, Mateusz; Gil, Malgorzata; Salisbury, Jeffrey L.; Goetz, Mathew P.; Suman, Vera; Degnim, Amy; McCubrey, James; Haddad, Tufia; Iankov, Ianko; Kurokawa, Chenye B.; Shumacher, Nicole; Ingle, James N.; Galanis, Evanthia; D’Assoro, Antonino B. (2017-09-01)
    Although the majority of breast cancers initially respond to the cytotoxic effects of chemotherapeutic agents, most breast cancer patients experience tumor relapse and ultimately die because of drug resistance. Breast ...