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Now showing items 131-140 of 173
Spontaneous bile duct perforation in a neonate
(2018-08-14)
We present a case of spontaneous biliary perforation (SBP) in a previously healthy 3-week-old boy with wor- sening scleral icterus, abdominal distension, and acholic stools. Abdominal ultrasound demonstrated moderate ascites ...
Bacteroides fragilis requires the ferrous-iron transporter FeoAB and the CobN-like proteins BtuS1 and BtuS2 for assimilation of iron released from heme
(2018-05-07)
The intestinal commensal and opportunistic anaerobic pathogen Bacteroides fragilis has an essential requirement for both heme and free iron to support growth in extraintestinal infections. In the absence of free iron, B. ...
Stem cell models of human synapse development and degeneration
(2018-11-26)
Many brain disorders exhibit altered synapse formation in development or syn- apse loss with age. To understand the complexities of human synapse development and degeneration, scientists now engineer neurons and brain ...
Step-wise evolution of complex chemical defenses in millipedes: a phylogenomic approach
(2018-02-16)
With fossil representatives from the Silurian capable of respiring atmospheric oxygen, millipedes
are among the oldest terrestrial animals, and likely the first to acquire diverse and complex chemical defenses against ...
TRANSHUMANISM, FRANKENSTEIN, AND EXTINCTION
(2018)
Shelley's novel has been fertile ground for ecocritics over the last two decades. In Ecocriticism and the Idea of Culture (2014, 2016) I wrote about Frankenstein and culture's dialectical horror of nature. As a narrative ...
Factors Associated with Discharge to a Skilled Nursing Facility after Transcatheter Aortic Valve Replacement Surgery
(2018-12-28)
An assumption regarding transcatheter aortic valve replacement (TAVR), a minimally invasive procedure for treating aortic stenosis, is that patients remain at, or near baseline and soon return to their presurgical home to ...
Diversity in warning coloration: selective paradox or the norm?
(2018-08-27)
Aposematic theory has historically predicted that predators should select for warning signals to converge on a single form, as a result of frequency‐dependent learning. However, widespread variation in warning signals is ...
Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics
(2018-11-14)
Missense mutations K15N and R21H in striated muscle tropomyosin are linked to dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), respectively. Tropomyosin, together with the troponin complex, regulates ...
Effectiveness of a Total Meal Replacement Program (OPTIFAST Program) on Weight Loss: Results from the OPTIWIN Study
(2018-11-13)
Objective: The aim of this study was to test the effectiveness of the OPTIFAST program (OP), a total meal replacement dietary intervention, compared with a food-based (FB) dietary plan for weight loss. Methods: Participants ...