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Behavioral and Transcriptome Profiling of Heterozygous Rab10 Knock-Out Mice
(2023-05-08)
A central question in the field of aging research is to identify the cellular and molecular basis of neuroresilience. One potential candidate is the small GTPase, Rab10. Here, we used Rab101/ mice to investigate the ...
Subtle alterations of vestibulomotor functioning in conductive hearing loss
(2023-08-29)
Introduction: Conductive hearing loss (CHL) attenuates the ability to transmit air conducted sounds to the ear. In humans, severe hearing loss is often accompanied by alterations to other neural systems, such as the ...
A SEER Database Retrospective Cohort of 547 Patients with Penile Non-Squamous Cell Carcinoma: Demographics, Clinical Characteristics, and Outcomes
(2023-10-31)
Introduction: Little research has investigated the prevalence and distribution of the diverse pathologies of non-squamous cell carcinoma (non-SCC) of the penis. Although rare in clinical practice, these cancers have become ...
m6A Regulates Breast Cancer Proliferation and Migration through Stage-dependent Changes in Epithelial to Mesenchymal Transition Gene Expression
(2023-11-07)
While many factors have been implicated in breast cancer progression, effective treatments are still lacking. In recent years, it has become clear that posttranscriptional regulation plays a key role in the aberrant gene ...
Collagen matricryptin promotes cardiac function by mediating scar formation
(2023-05-15)
Aims
A peptide mimetic of a collagen-derived matricryptin (p1159) was shown to reduce left ventricular (LV) dilation and fibrosis after 7 days delivery in a mouse model of myocardial infarction (MI). This suggested p1159 ...
Apoptosis mechanisms induced by 15d-PMJ2 in HCT116 colon cancer cells: insights into CHOP10/TRB3/Akt signaling
(2023-11-02)
Agents that stimulate the endoplasmic reticulum (ER) stress pathway are being exploited pharmacologically to induce cancer cell death. Cytotoxic ER stress is typically regulated by the transcription factor, C/EBP homologous ...
How do we best support adolescents with low academic performance and learning disabilities in the era of pandemic learning loss? The importance of intensive learning strategy interventions
(2023-11-02)
The COVID-19 pandemic put a spotlight on learning loss that teachers of low-performing adolescents, including those with learning disabilities (LD), have confronted for decades. Federal funding offers opportunities for ...
Immigration from Africa to the United States: key insights from recent research
(2023-06-08)
Immigration from Africa to the United States has increased dramatically in the past three decades. This paper summarizes recent findings on the growth of African immigration to the United States in recent years. In doing ...
The Use of Teledentistry in Clinical Oral and Maxillofacial Pathology Practice: An Institutional Experience
(2023-07-20)
Background: Although there has been a slight increase in dental professionals since 2011, 98 of North Carolina's 100 counties are designated as Dental Health Professional Shortage Areas by the Heath Resources and Service ...
Similarities and Differences Regarding Acute Anorexia Nervosa and Semi-starvation: Does Behavioral Thermoregulation Play a Central Role?"
(2023-10-25)
Objective: To clarify the association between acute anorexia nervosa (AN) and semi-starvation (SS) by focusing on similarities and differences in physiology, mood, and behavior.
Method: A comparison of published literature ...