Browsing Health Sciences Campus by Author "Chitwood, W. Randolph"
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Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model
Hopson, Steven B.; Lust, Robert M.; Sun, You Su; Zeri, Richard S.; Morrison, Ron F.; Otaki, Masaki; Chitwood, W. Randolph (East Carolina University, 1995-07)The ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (XO)- inhibiting properties. Human myocardium how- ever, has exhibited low levels of XO ... -
Comparison of a New bioprosthetic Mitral Valve to Other Commercially Available Devices Under Controlled Conditions in a Porcine Mode
Chitwood, W. Randolph; Wang, Dee Dee; Caranasos, Thomas G.; O'Neill, Brian P.; Stack, Richard S.; O'Neill, William W. (2021) -
Discharge β-Blocker Use and Race after Coronary Artery Bypass Grafting
O'Neal, Wesley T.; Efird, Jimmy T.; Davies, Stephen W.; O'Neal, Jason B.; Griffin, William F.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2014-04)Introduction: The use of discharge β-blockers after cardiac surgery is associated with a long-term mortality benefit. β-Blockers have been suggested to be less effective in black cardiovascular patients compared with whites. ... -
The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting
Efird, Jimmy T.; O'Neal, Wesley T.; Anderson, Curtis A.; O'Neal, Jason B.; Kindell, Linda C.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2013-04)Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: ... -
Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents
Efird, Jimmy T.; Griffin, William F.; Sarpong, Daniel F.; Davies, Stephen W.; Vann, Iulia; Koutlas, Nathaniel T.; Anderson, Ethan; Crane, Patricia B.; Landrine, Hope; Kindell, Linda C.; Iqbal, Zahra J.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2015-07)The aim of this study was to examine racial differences in long-term mortality after coronary artery bypass grafting (CABG), stratified by preoperative use of inotropic agents. Black and white patients who required ... -
Monoamine Oxidase is a Major Determinant of Redox Balance in Human Atrial Myocardium and is Associated With Postoperative Atrial Fibrillation
Anderson, Ethan; Efird, Jimmy T.; Davies, Stephen W.; O'Neal, Wesley T.; Darden, Timothy M.; Thayne, Kathleen A.; Katunga, Lalage Adalaide; Kindell, Linda C.; Ferguson, T. Bruce; Anderson, Curtis A.; Chitwood, W. Randolph; Koutlas, Theodore C.; Williams, J. Mark; Rodriguez, Evelio; Kypson, Alan P. (2014-02)BACKGROUND: Onset of postoperative atrial fibrillation (POAF) is a common and costly complication of heart surgery despite major improvements in surgical technique and quality of patient care. The etiology of POAF, and ... -
Racial Differences in Survival among Hemodialysis Patients after Coronary Artery Bypass Grafting
Efird, Jimmy T.; O'Neal, Wesley T.; Bolin, Paul Jr.; Davies, Stephen W.; O'Neal, Jason B.; Anderson, Curtis A.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2013-09)The aim of this study was to examine racial differences in long-term survival among hemodialysis patients after coronary artery bypass grafting (CABG). To our knowledge this has not been previously addressed in the literature. ... -
Risk-Adjusted Survival after Coronary Artery Bypass Grafting: Implications for Quality Improvement
Efird, Jimmy T.; O'Neal, Wesley T.; Davies, Stephen W.; O'Neal, Jason B.; Kindell, Linda C.; Anderson, Curtis A.; Chitwood, W. Randolph; Ferguson, T. Bruce; Kypson, Alan P. (2014-07)Mortality represents an important outcome measure following coronary artery bypass grafting. Shorter survival times may reflect poor surgical quality and an increased number of costly postoperative complications. Quality ... -
Robotic Surgical Training in an Academic Institution
Chitwood, W. Randolph; Nifong, L. Wiley; Chapman, William H. H.; Felger, Jason E.; Bailey, B. Marcus; Ballint, Tara; Mendleson, Kim G.; Kim, Victor B.; Young, James A.; Albrecht, Robert A. (East Carolina University, 2001-10)Objective To detail robotic procedure development and clinical applications for mitral valve, biliary, and gastric reflux operations, and to implement a multispecialty robotic surgery training curriculum for both ...