Browsing Health Sciences Campus by Author "Farrow, John M. III"

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  • PqsE Functions Independently of PqsR-Pseudomonas Quinolone Signal and Enhances the rhl Quorum-Sensing System 

    Farrow, John M. III; Sund, Zoe M.; Ellison, Matthew L.; Wade, Dana S.; Coleman, James P.; Pesci, Everett C. (East Carolina University, 2008-11)
    Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute and chronic infections in immunocompromised individuals. This gram-negative bacterium produces a battery of virulence factors that allow it to ...

  • Pseudomonas aeruginosa PqsA Is an Anthranilate-Coenzyme A Ligase 

    Coleman, James P.; Hudson, L. Lynn; McKnight, Susan L.; Farrow, John M. III; Calfee, M. Worth; Lindsey, Claire A.; Pesci, Everett C. (East Carolina University, 2008-02)
    Pseudomonas aeruginosa is an opportunistic human pathogen which relies on several intercellular signaling systems for optimum population density-dependent regulation of virulence genes. The Pseudomonas quinolone signal ...

  • Two Distinct Pathways Supply Anthranilate as a Precursor of the Pseudomonas Quinolone Signal 

    Farrow, John M. III; Pesci, Everett (East Carolina University, 2007-05)
    Pseudomonas aeruginosa is an opportunistic pathogen that causes serious infections in immunocompromised patients and those with cystic fibrosis (CF). This gram-negative bacterium uses multiple cell-to-cell signals to control ...