Browsing Health Sciences Campus by Author "Thayne, Kathleen A."
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Monoamine Oxidase is a Major Determinant of Redox Balance in Human Atrial Myocardium and is Associated With Postoperative Atrial Fibrillation
Anderson, Ethan; Efird, Jimmy T.; Davies, Stephen W.; O'Neal, Wesley T.; Darden, Timothy M.; Thayne, Kathleen A.; Katunga, Lalage Adalaide; Kindell, Linda C.; Ferguson, T. Bruce; Anderson, Curtis A.; Chitwood, W. Randolph; Koutlas, Theodore C.; Williams, J. Mark; Rodriguez, Evelio; Kypson, Alan P. (2014-02)BACKGROUND: Onset of postoperative atrial fibrillation (POAF) is a common and costly complication of heart surgery despite major improvements in surgical technique and quality of patient care. The etiology of POAF, and ... -
Obesity in a model of haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
Katunga, Lalage Adalaide; Gudimella, Preeti; Efird, Jimmy T.; Abernathy, Scott; Mattox, Taylor A.; Beatty, Cherese; Darden, Timothy M.; Thayne, Kathleen A.; Alwair, Hazaim; Kypson, Alan P.; Virag, Jitka A. I.; Anderson, Ethan (2015-04)Lipid peroxides and their reactive aldehyde derivatives (LPPs) have been linked to obesity-related pathologies, but whether they have a causal role has remained unclear. Glutathione peroxidase 4 (GPx4) is a selenoenzyme ...