Browsing Brody School of Medicine by Title
Now showing items 918-937 of 1483
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Much to consider about multivitamin-mineral supplements
(2023-06-28)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column shares some of the information presented at the Council on Aging's Brainiac Bootcamp and answers a question about multiple ... -
Multi-spectral physiologic visualization (MSPV) using laser imaging methods and systems for blood flow and perfusion imaging and quantification in an endoscopic design
(2017-08-28)Multispectral imaging systems are provided including a first light source having a first wavelength configured to image a sample; a second light source, different from the first light source, having a second wavelength, ... -
Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice
(2011)Background Multi-walled carbon nanotubes (MWCNTs) are widely used in many disciplines due to their unique physical and chemical properties. Therefore, some concerns about the possible human health and environmental ... -
Multicenter Trial of Sentinel Node Biopsy for Breast Cancer Using Both Technetium Sulfur Colloid and Isosulfan Blue Dye
(East Carolina University, 2001-01)Objective To determine the factors associated with false-negative results on sentinel node biopsy and sentinel node localization (identification rate) in patients with breast cancer enrolled in a multicenter ... -
A Multicomponent System Is Required for Tetracycline-Induced Excision of Tn4555
(East Carolina University, 2004-01)Bacteroides spp. are the predominant organisms in the intestinal tract, and they also are important opportunistic pathogens. Antibiotic therapy of Bacteroides infections often is complicated by the prevalence of drug-resistant ... -
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
(2014-01)Glycogen synthase kinase-3 (GSK-3) is well documented to participate in a complex array of critical cellular processes. It was initially identified in rat skeletal muscle as a serine/threonine kinase that phosphorylated ... -
Multiple Kinase Involvement in the Regulation of Vascular Growth
(New York: InTech Open Access Publishers, 2012-06)The initial discovery of protein phosphorylation as a regulatory mechanism for the control of glycogen metabolism has led to intense interest of protein phosphorylation in regulating protein function (Cohen et al., 2001). ... -
Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications
(1999-03-25)Antisense oligonucleotides which bind to two or more RNA targets are disclosed. -
Multiple Translation Factor eIF4G (IFG-1) Isoforms are Required for the Apoptosome-Dependent Activation of Germ Cell Apoptosis
(East Carolina University, 2010)Apoptosis is a naturally occurring process during animal development required for the programmed killing and removal of injured cells. Cellular insult induces a switch in translation that allows for the rapid synthesis ... -
MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo
(2014-06)MuRF1 is a previously reported ubiquitin-ligase found in striated muscle that targets troponin I and myosin heavy chain for degradation. While MuRF1 has been reported to interact with mitochondrial substrates in yeast ... -
Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer
(2016-03)Background Mesothelin has attracted much interest as a tumor specific antigen; it has been reported to promote tumor development and to be a good target for cancer treatment. Most studies to date have used human mesothelin ... -
Murine Pancreatic Adenocarcinoma Reduces Ikaros Expression and Disrupts T Cell Homeostasis
(2015-01)Background Maintenance of T cell immune homeostasis is critical for adequate anti-tumor immunity. The transcription factor Ikaros is essential for lymphocyte development including T cells. Alterations in Ikaros expression ... -
Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment
(2015-05)Recent strategies to treat peripheral arterial disease (PAD) have focused on stem cell based therapies, which are believed to result in local secretion of vascular growth factors. Little is known, however, about the role ... -
Muscle Mitochondria in Vascular Disease: A Novel Genetic Target for Limb Salvage
(East Carolina University, 2022-04-19)Peripheral arterial occlusive disease (PAD) is a manifestation of systemic atherosclerosis defined by an occlusion in the peripheral arteries, most commonly those supplying blood to the lower extremities. Chronic limb ... -
Mushrooms may be good medicine
(2020-09-09)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column is about medicinal mushrooms and some if the potential benefits and risks, especially related to cancer and neurogenerative ... -
Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response
(2012-09)The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Certain components of these pathways, RAS, NF1, BRAF, ...