Browsing Brody School of Medicine by Author "Knudson, Cheryl B."
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A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS
Sellers, Samantha Sue (East Carolina University, 2017-07-13)During embryogenesis, mesenchymal progenitor cells exhibit hyaluronan-dependent pericellular matrices as a major component of the extracellular matrix. As connective tissues form by cellular condensations, there is a loss ... -
CD44 and hyaluronan promote the bmp7 signaling response in chondrocytes
Luo, Na (East Carolina University, 2011)Cell-matrix interactions are important in maintaining cartilage homeostasis. Hyaluronan binding to its principal receptor CD44 is essential for such interactions. Hyaluronan-CD44 interactions are required for the retention ... -
Chondroprotective Effect of Kartogenin on CD44-Mediated Functions in Articular Cartilage and Chondrocytes
Ono, Yohei; Ishizuka, Shinya; Knudson, Cheryl B.; Knudson, Warren (2014-07) -
Hyaluronan Oligosaccharides Inhibit Tumorigenicity of Osteosarcoma Cell Lines MG-63 and LM-8 in Vitro and in Vivo via Perturbation of Hyaluronan-Rich Pericellular Matrix of the Cells
Hosono, Kozo; Nishida, Yoshihiro; Knudson, Warren; Knudson, Cheryl B.; Naruse, Takahiro; Suzuki, Yoshitaka; Ishiguro, Naoki (East Carolina University, 2007-07)Numerous studies have demonstrated a correlation between hyaluronan expression and the malignant properties of various kinds of cancer , and inhibition of hyaluronan production causes decreased tumor growth. Hyaluronan ... -
Metabolic Reprogramming in Chondrocytes to Promote Mitochondrial Respiration Reduces Downstream Features of Osteoarthritis
Knudson, Cheryl B.; Knudson, Warren; Ohashi, Yoshifumi; Takahashi, Nobunori; Terabe, Kenya; Tsuchiya, Saho; Kojima, Toshihisa; Imagama, Shiro (2021)