Browsing Brody School of Medicine by Author "Ruiz-Echevarria, Maria"
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An examination of the functional role of TMEFF2 in prostate cancer and the translational regulatory mechanisms controlling its expression
Overcash, Ryan Franklin (East Carolina University, 2012)Prostate cancer is the most commonly diagnosed cancer in American men and accounts for approximately 11% of cancer-related deaths. Although promising treatment strategies have been developed and are currently being tested ... -
Molecular mechanisms of TMEFF2 action in Prostate Cancer
Chen, Xiaofei (East Carolina University, 2013)The transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) is an evolutionarily conserved type I transmembrane protein expressed in the embryo and limited adult tissues, mainly the brain ... -
TMEFF2 is an epigenetic modulator that promotes androgen independent growth in castration-resistant prostate cancer cells
Corbin, Joshua Moses (East Carolina University, 2014)While the ability to detect PCa has improved significantly due to PSA screenings, the survival rate for men diagnosed with PCa has remained stagnant, and the disease remains the second leading cause of cancer related deaths ...