Browsing Brody School of Medicine by Subject "IGF-1R"
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Enforced expression of HoxA9 in b-lineage all promotes survival and proliferation of leukemic cells (East Carolina University, 2009)HoxA9 is frequently overexpressed in acute myeloid leukemia, myelodysplastic syndrome and a subset of acute lymphoblastic leukemia. In mouse models, HoxA9 has been shown to promote leukemogenesis. In spite of a seemingly ...