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The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
(2013)
BACKGROUND:
Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ...
Prolactin and Dehydroepiandrosterone Levels in Women with Systemic Lupus Erythematosus: The Role of the Extrapituitary Prolactin Promoter Polymorphism at −1149G/T
(2015)
stemic lupus erythematosus (SLE) has shown an association with high levels of prolactin, low levels of dehydroepiandrosterone (DHEA), and induction of inflammatory cytokines in the serum of patients with the disease. This ...
Review of Musculoskeletal Injuries and Prevention in the Endoscopy Practitioner
(2014-08)
Practitioners of endoscopy often experience musculoskeletal pain and injury (most often in the back, neck, shoulders, hands, wrists, and thumbs) that are associated with the minute and repetitive strain that is placed on ...
Spontaneous Weight Change during Chronic Hepatitis C Treatment: Association with Virologic Response Rates
(2013)
Objective: We examined weight changes during chronic hepatitis C (CHC) therapy and association with virologic response.
Methods: Weight changes were compared between subjects achieving rapid, early, and sustained virologic ...
Transplant Coordinators' Perceived Impact of Availability of Multiple Generic Immunosuppression Therapies on Patients, Workload, and Posttransplant Maintenance Therapy
(2013)
Background. No studies have evaluated the impact of multiple generic immunosuppression medications on transplant coordinators (TCs) and patients. Methods. A cross-sectional, multicenter online survey of TCs managing ...
Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment
(2015-05)
Cancer cells preferentially utilize glycolysis, instead of oxidative phosphorylation, for metabolism even in the presence of oxygen. This phenomenon of aerobic glycolysis, referred to as the “Warburg effect”, commonly ...
Challenges and Solutions in the Development of Genomic Biomarker Panels: A Systematic Phased Approach
(2012-06)
In the post-genome era, high throughput gene expression profiling has been successfully used to develop genomic biomarker panels (GBP) that can be integrated into clinical decision making. The development of GBPs in the ...
MicroRNA profiling in the left atrium in patients with non-valvular paroxysmal atrial fibrillation
(2015-08)
Background
We aimed to identify the miRNA expression profiles in left atrial appendage, with the intention of identifying miRNAs that were significantly associated with non-valvular paroxysmal AF.
Methods
The RNA ...
Postpartum spontaneous dissection of the first obtuse marginal branch of the left circumflex coronary artery causing acute coronary syndrome: a case report and literature review
(2013)
Spontaneous coronary artery dissection (SCAD) is a very rare cause of acute coronary syndromes in young otherwise healthy patients with a striking predilection for the female gender. The pathological mechanism has not been ...