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The effect of fasting on the activation in vivo of the insulin receptor kinase.
(East Carolina University, 1990-02-01)
Fasting causes insulin resistance in liver and fat, and increases insulin sensitivity in muscle. We studied the response in vitro and in vivo to insulin of the insulin receptor tyrosine kinase in muscle and liver from 72 ...
Tinigible Body Macrophages in Regulation of Germinal Center Reactions
(East Carolina University, 1998)
Tingible body macrophages (TBM), long thought simply as scavengers of apoptotic lymphocytes, are located in the unique microenvironment of germinal centers in close proximity to antigen-retaining follicular dendritic cells ...
Prenatal diagnosis of a giant intracranial teratoma associated with pulmonary hypoplasia.
(East Carolina University, 1993-10)
We present a case in which an intracranial tumour replacing all intracranial contents was diagnosed by sonography at 31 weeks' gestation. The patient was delivered by caesarean section and died shortly after delivery. At ...
Response to Kuhse
(East Carolina University, 2002-08)
In this short paper, we respond to critics of our original paper, The agony of agonal respiration: is the
last gasp necessary?. A common thread in both Hawryluckâ s and Kuhseâ s responses is the difficulties
encountered ...
Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner
(East Carolina University, 2010-04-12)
Background: Elevated levels of air pollution are associated with increased risk of lung cancer. Particulate matter (PM)
contains transition metals that may potentiate neoplastic development through the induction of oxidative ...
Small Molecule, Non-Peptide p75NTR Ligands Inhibit Aß-Induced Neurodegeneration and Synaptic Impairment
(East Carolina University, 2008-11-03)
The p75 neurotrophin receptor (p75NTR) is expressed by neurons particularly vulnerable in Alzheimer’s disease (AD). We tested
the hypothesis that non-peptide, small molecule p75NTR ligands found to promote survival signaling ...
YC-1 Stimulates the Expression of Gaseous Monoxide-Generating Enzymes in Vascular Smooth Muscle Cells
(East Carolina University, 2009-01)
The benzylindazole derivative 3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole (YC-1) is an allosteric stimulator of soluble guanylate cyclase (sGC) that sensitizes the enzyme to the gaseous ligands carbon monoxide (CO) and ...
Lymphocytic hypophysitis.
(East Carolina University, 1994-05)
LYMPHOCYTIC HYPOPHYSITIS is an unusual disorder that nearly exclusively affects women; fewer than 50 cases have been reported in the literature. The present case also is unusual because a normal computed tomographic (CT) ...
Cocaine Disrupts Pup-Induced Maternal Behavior in Juvenile and Adult Rats
(East Carolina University, 2007-11)
Impaired onset of maternal behavior in first generation rat dams was previously correlated with rearing by cocaine-treated dams and prenatal cocaine exposure. Pup-induced maternal behavior in non-lactating rats has not ...
Cranial Ultrasound Lesions in the NICU Predict Cerebral Palsy at Age 2 Years in Children Born at Extremely Low Gestational Age
(East Carolina University, 2009-01)
Our prospective cohort study of extremely low gestational age newborns evaluated the association of neonatal head ultrasound abnormalities with cerebral palsy at age 2 years. Cranial ultrasounds in 1053 infants were read ...