Now showing items 1-3 of 3
Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma
NECL-5 is involved in regulating cell–cell junctions, in cooperation with cadherins, integrins and platelet-derived growth factor receptor, that are essential for intercellular communication. Its role in malignant ...
Analysis of the mutation in cutaneous melanoma patients with occupational sun exposure
Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including ...
Emerging targeted therapies for melanoma treatment (Review)
Cutaneous melanoma is an aggressive cancer with a poor prognosis for patients with advanced disease. The identification of several key molecular pathways implicated in the pathogenesis of melanoma has led to the development ...