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Inhibition by rapamycin of ornithine decarboxylase and epithelial cell proliferation in intestinal IEC-6 cells in culture
(East Carolina University, 1997-02)
1 Induction of the enzyme ornithine decarboxylase (ODC) appears to be controlled primarily at the
level of ODC mRNA translation. The immunosuppressant drug, rapamycin, blocked the induction of
ODC in response to serum ...