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Extracellular matrix induction method to produce pancreatic islet tissue
(1990-06-19)
A method and composition of regenerating tissue. More specifically, a method for regenerating pancreatic islet tissue having the histological and insulin-containing properties of islets typically found in neonatal or adult ...
QUANTITATION OF INTERCELLULAR CONNECTIONS BETWEEN SPERMATOGONIA IN THE MOUSE
(East Carolina University, 2017-05-09)
Spermatogonial stem cells (SSCs) are critical in the male reproductive process, as they can either self-renew or proliferate into progenitor cells that differentiate to enter meiosis and eventually form functional sperm. ...
Do Pesticides cause Obesity and Diabetes?
(2019-08-05)
We have an epidemic of obesity that presents with serious health and economic consequences.
Obesity is the most common disease in the U.S. that has developed rapidly in only a matter of decades.
Glyphosate (RoundupTM) ...
The therapeutic effect of Rho kinase inhibitor Y-27632 on protection from chemotherapy-induced peripheral neuropathy
(2018-04-17)
Cisplatin often causes loss of touch sensitivity in the hands and feet of cancer patients as well as tingling, numbness, and a shooting or burning pain; these clinical symptoms are referred to as chemotherapy-induced ...
The therapeutic effect of Rho kinase inhibitor Y-27632 on protection from chemotherapy-induced peripheral neuropathy
(2018-03-26)
Cisplatin often causes loss of touch sensitivity in the hands and feet of cancer patients as well as tingling, numbness, and a shooting or burning pain; these clinical symptoms are referred to as chemotherapy-induced ...
PPP1R42 is a positive regulator of PP1 in centrosome duplication and separation and cilia dynamics
(East Carolina University, 2014)
The centrosome is a dynamic structure that undergoes structural and functional transitions, which are coordinated with the cell cycle. It functions as the microtubule organizing center (MTOC) in interphase, duplicates and ...
A non-tight junction function of claudin-7—Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment
(2015-06-17)
Background
Claudins are a family of tight junction (TJ) membrane proteins involved in a broad spectrum of human diseases including cancer. Claudin-7 is a unique TJ membrane protein in that it has a strong basolateral ...