Browsing Open Access by Author "Malur, Anagha"

Now showing items 1-3 of 3

  • Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis 

    Malur, Anagha; Kavuru, Mani S; Marshall, Irene; Barna, Barbara P.; Huizar, Isham; Karnekar, Reema; Thomassen, Mary Jane (2012-06-14)
    Pulmonary Alveolar Proteinosis (PAP) patients exhibit an acquired deficiency of biologically active granulocyte-macrophage colony stimulating factor (GM-CSF) attributable to GM-CSF specific autoantibodies. PAP alveolar ...

  • The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation 

    Huizar, Isham; Malur, Anagha; Patel, Janki; McPeek, Matthew; Dobbs, Larry; Wingard, Christopher; Barna, Barbara P.; Thomassen, Mary Jane (2013-01-23)
    Background Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly understood. Carbon nanoparticles, which can be products ...

  • Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells 

    Gharib, Sina A.; Malur, Anagha; Huizar, Isham; Barna, Barbara P.; Kavuru, Mani S.; Schnapp, Lynn M.; Thomassen, Mary Jane (2016-07)
    Background: Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most commonly involves the lungs. We hypothesized that an unbiased approach to identify pathways activated in bronchoalveolar ...