Browsing Open Access by Author "Schwalbe, Ruth A."
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Complex N-Glycans Influence the Spatial Arrangement of Voltage Gated Potassium Channels in Membranes of Neuronal-Derived Cells
Hall, Kristen; Weidner, Douglas A.; Edwards, Michael A. J.; Schwalbe, Ruth A. (2015-09-08)The intrinsic electrical properties of a neuron depend on expression of voltage gated potassium (Kv) channel isoforms, as well as their distribution and density in the plasma membrane. Recently, we showed that N-glycosylation ... -
Glycan Structures Contain Information for the Spatial Arrangement of Glycoproteins in the Plasma Membrane
Hall, M. Kristen; Weidner, Douglas A.; Chen, Jian ming; Bernetski, Christopher J.; Schwalbe, Ruth A. (2013-09-06)Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information ... -
Importance of glycosylation on function of a potassium channel in neuroblastoma cells
Hall, M K; Cartwright, Tara A.; Fleming, Christa M.; Schwalbe, Ruth A. (2011-04)The Kv3.1 glycoprotein, a voltage-gated potassium channel, is expressed throughout the central nervous system. The role of N-glycans attached to the Kv3.1 glycoprotein on conducting and non-conducting functions of the Kv3.1 ...