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Evaluating Multipulse Integration as a Neural-Health Correlate in Human Cochlear-Implant Users: Relationship to Psychometric Functions for Detection
(2017-01)
In electrical hearing, multipulse integration (MPI) describes the rate at which detection threshold decreases with increasing stimulation rate in a fixed-duration pulse train. In human subjects, MPI has been shown to be ...
Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies
(2017-12)
Background: Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progres‐ ...
Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells
(2017-01-27)
Acidosis commonly exists in the tissue microenvironment of various pathophysiological conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory disease. For instance, the tumor microenvironment ...