Search
Now showing items 1-2 of 2
Emerging roles for the pH-sensing G protein-coupled receptors in response to acidotic stress
(2015)
Protons (hydrogen ions) are the simplest form of ions universally produced by cellular metabolism including aerobic respiration and glycolysis. Export of protons out of cells by a number of acid transporters is essential ...
Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies
(2017-12)
Background: Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progres‐ ...