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Coagulation Factor XIIIa Undergoes a Conformational Change Evoked by Glutamine Substrate

Mitkevich, Olga; Teller, David C.; Bishop, Paul D.; Yee, Vivian; Smejkal, Gary B.; Shainoff, John R.; Samokhin, Gennady P. (1988-06-05)

Coagulation factor XIIIa, plasma transglutaminase(endo-g-glutamine:e-lysine transferase EC 2.3.2.13) cata-lyzes isopeptide bond formation between glutamine andlysine residues and rapidly cross-links fibrin clots. ...