Browsing Biochemistry and Molecular Biology by Author "Contreras, Vince"
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Cap-Independent Translation Promotes Germ Cell Apoptosis through Apaf-1/CED-4 in a Caspase-Dependent Mechanism
Contreras, Vince; Friday, Andrew J.; Morrison, J. Kaitlin; Hao, Enhui; Keiper, Brett D. (2011) -
A germline-specific isoform of eIF4E (IFE-1) is required for efficient translation of stored mRNAs and maturation of both oocytes and sperm
Henderson, Melissa Anne; Cronland, Elizabeth; Dunkelbarger, Steve; Contreras, Vince; Strome, Susan; Keiper, Brett D. (East Carolina University, 2009-05-15)Fertility and embryonic viability are measures of efficient germ cell growth and development. During oogenesis and spermatogenesis, new proteins are required for both mitotic expansion and differentiation. Qualitative and ... -
Multiple Translation Factor eIF4G (IFG-1) Isoforms are Required for the Apoptosome-Dependent Activation of Germ Cell Apoptosis
Contreras, Vince (East Carolina University, 2010)Apoptosis is a naturally occurring process during animal development required for the programmed killing and removal of injured cells. Cellular insult induces a switch in translation that allows for the rapid synthesis ...