Now showing items 1-9 of 9

  • Catabolite repression control (crc) gene and pseudomonas virulence 

    Phibbs, Paul; Collier, David N.; Hager, Paul (2002-08-22)
    A method of screening for compounds that inhibit the virulence of Pseudomonas bacteria comprises the steps of: providing a culture medium comprising Pseudomonas bacteria; administering a test compound to said bacteria; and ...
  • Composition and formulations and their use as nociceptic, anti-anxiolytic and anabolic agents 

    Nyce, Jonathan W. (2000-07-13)
    Composition and formulations comprising a first agent such as folinic acid, pharmaceutically acceptable salts thereof or mixtures thereof, and a second agent(s) such as analgesics, muscle relaxants, mood disorder agents, ...
  • Disruption of pqs synthesis using precursor analogs 

    Pesci, Everett; Coleman, James P. (2004-01-08)
    The present invention concerns methods of detecting bacterial infections as well as methods of treating such infections with compounds such as methyl anthranilate. The detection and treatment of Pseudomonas is particularly ...
  • Erythropoietin ameliorates chemotherapy-induced toxicity in vivo 

    Sigounas, George; Mehlhop, Paul (2002-10-17)
    A method of reducing organ toxicity in a subject being administered a cytotoxic agent comprising concurrently administering with the cytotoxic agent erythropoietin (EPO), the EPO being administered in an amount effective ...
  • Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments 

    Nyce, Jonathan W. (2000-02-24)
    A composition comprises a nucleic acid comprising an oligo anti-sense to a target such as polypeptide(s) associated with an ailment afflicting lung airways, genes and mRNAs encoding them, genomic and mRNA flanking regions, ...
  • Measles vaccine vectors and methods of use 

    Ross, Ted; Robinson, Harriet (2003-03-20)
    The present invention provides a novel vaccine expressing a fusion of the measles hemagglutinin (H) protein and the complement component, C3d, to enhance the titers of neutralizing antibody. Plasmids were generated that ...
  • Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds 

    Hayford, Anthony; Kaloko, Joseph (2006-07-13)
    A method of making a compound of Formula (I) comprises reacting a compound of Formula (II) with a compound such as R1OH or R1SH, to produce said compound of Formula (I). Compounds of Formula (I) are useful, among other ...
  • NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease 

    Cistola, David; Robinson, Michelle (2017-01-14)
    A method is disclosed for measuring the properties of protein and lipoprotein elements in a sample. The method includes the of placing a small volume of a sample into a NMR instrument tuned to measure a particular nucleus, ...
  • Novel autoinducer molecules and uses therefor 

    Greenberg, Everett; Iglewski, Barbara; Kende, Andrew; Milbank, Jared B. J.; Pearson, James P.; Pesci, Everett (2002-03-07)
    Novel bacterial quinolone signal molecules and, more particularly, pseudomonas quinolone signal ('PQS') molecules, e.g., 2-heptyl-3hydroxy-4-quinolone, and analogs and derivatives thereof are described, Therapeutic ...