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    Feasibility of Tomotherapy-Based Image-Guided Radiotherapy to Reduce Aspiration Risk in Patients with Non-Laryngeal and Non-Pharyngeal Head and Neck Cancer

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    Author
    Nguyen, Nam P.; Smith-Raymond, Lexie; Vinh-Hung, Vincent; Vos, Paul; Davis, Rick; Desai, Anand; Sroka, Thomas; Abraham, Dave; Krafft, Shane P.; Stevie, Michelle; Modarresifar, Homayoun; Jo, Beng-Hoey; Ceizyk, Misty
    Abstract
    PURPOSE: The study aims to assess the feasibility of Tomotherapy-based image-guided radiotherapy (IGRT) to reduce the aspiration risk in patients with non-laryngeal and non-hypopharyngeal cancer. A retrospective review of 48 patients undergoing radiation for non-laryngeal and non-hypopharyngeal head and neck cancers was conducted. All patients had a modified barium swallow (MBS) prior to treatment, which was repeated one month following radiotherapy. Mean middle and inferior pharyngeal dose was recorded and correlated with the MBS results to determine aspiration risk. RESULTS: Mean pharyngeal dose was 23.2 Gy for the whole group. Two patients (4.2%) developed trace aspiration following radiotherapy which resolved with swallowing therapy. At a median follow-up of 19 months (1-48 months), all patients were able to resume normal oral feeding without aspiration. CONCLUSION AND CLINICAL RELEVANCE: IGRT may reduce the aspiration risk by decreasing the mean pharyngeal dose in the presence of large cervical lymph nodes. Further prospective studies with IGRT should be performed in patients with non-laryngeal and non-hypopharyngeal head and neck cancers to verify this hypothesis.
    URI
    http://hdl.handle.net/10342/7776
    Date
    2013-03-07
    Citation:
    APA:
    Nguyen, Nam P., & Smith-Raymond, Lexie, & Vinh-Hung, Vincent, & Vos, Paul, & Davis, Rick, & Desai, Anand, & Sroka, Thomas, & Abraham, Dave, & Krafft, Shane P., & Stevie, Michelle, & Modarresifar, Homayoun, & Jo, Beng-Hoey, & Ceizyk, Misty. (March 2013). Feasibility of Tomotherapy-Based Image-Guided Radiotherapy to Reduce Aspiration Risk in Patients with Non-Laryngeal and Non-Pharyngeal Head and Neck Cancer. PLoS ONE, (8:3), p.1-7. Retrieved from http://hdl.handle.net/10342/7776

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    MLA:
    Nguyen, Nam P., and Smith-Raymond, Lexie, and Vinh-Hung, Vincent, and Vos, Paul, and Davis, Rick, and Desai, Anand, and Sroka, Thomas, and Abraham, Dave, and Krafft, Shane P., and Stevie, Michelle, and Modarresifar, Homayoun, and Jo, Beng-Hoey, and Ceizyk, Misty. "Feasibility of Tomotherapy-Based Image-Guided Radiotherapy to Reduce Aspiration Risk in Patients with Non-Laryngeal and Non-Pharyngeal Head and Neck Cancer". PLoS ONE. 8:3. (1-7.), March 2013. February 28, 2021. http://hdl.handle.net/10342/7776.
    Chicago:
    Nguyen, Nam P. and Smith-Raymond, Lexie and Vinh-Hung, Vincent and Vos, Paul and Davis, Rick and Desai, Anand and Sroka, Thomas and Abraham, Dave and Krafft, Shane P. and Stevie, Michelle and Modarresifar, Homayoun and Jo, Beng-Hoey and Ceizyk, Misty, "Feasibility of Tomotherapy-Based Image-Guided Radiotherapy to Reduce Aspiration Risk in Patients with Non-Laryngeal and Non-Pharyngeal Head and Neck Cancer," PLoS ONE 8, no. 3 (March 2013), http://hdl.handle.net/10342/7776 (accessed February 28, 2021).
    AMA:
    Nguyen, Nam P., Smith-Raymond, Lexie, Vinh-Hung, Vincent, Vos, Paul, Davis, Rick, Desai, Anand, Sroka, Thomas, Abraham, Dave, Krafft, Shane P., Stevie, Michelle, Modarresifar, Homayoun, Jo, Beng-Hoey, Ceizyk, Misty. Feasibility of Tomotherapy-Based Image-Guided Radiotherapy to Reduce Aspiration Risk in Patients with Non-Laryngeal and Non-Pharyngeal Head and Neck Cancer. PLoS ONE. March 2013; 8(3) 1-7. http://hdl.handle.net/10342/7776. Accessed February 28, 2021.
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