Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis
Author
Abdelfatah, Mohamed M.; Koutlas, Nicholas J.; Gochanour, Eric; Hamed, Ahmed; Ibrahim, Mariam; Barakat, Mohamed; Mudireddy, Prashant R.
Abstract
Background: Pancreatitis is a potential major complication after endoscopic retrograde
cholangiopancreatography (post-ERCP pancreatitis; PEP). Obesity has been associated with
increased severity of acute pancreatitis. However, the correlation between obesity and PEP is
controversial. Therefore, our study aimed to clarify the relationship between body mass index
(BMI) and the incidence and severity of PEP.
Methods: A retrospective cohort study was conducted to elucidate the relationship between BMI
and PEP in all patients who underwent ERCP in a tertiary referral center between January 2009
and October 2016. Patient characteristics and procedure details were collected. PEP was defined
by consensus criteria. Multivariate logistic regression was used to determine the association
between BMI and PEP.
Results: The analysis included 2236 patients whose BMI was recorded and had adequate follow up
(921 with BMI≥30 kg/m2, 1315 with BMI<30 kg/m2). PEP was diagnosed in 107 (4.8%) patients.
PEP was seen in 49 obese patients (5.3%) and 58 non-obese patients (4.4%). In the univariate and
multivariate analysis BMI≥30 kg/m2 was not associated with PEP (odds ratio 1.2, 95%CI 0.8-1.8;
P=0.32). A subgroup analysis of different BMI subcategories found that BMI was not associated
with the incidence or severity of PEP.
Conclusion: In the largest study to date, neither obesity nor low body weight increased the
incidence or severity of PEP.
Date
2019-03-12
Citation:
APA:
Abdelfatah, Mohamed M., & Koutlas, Nicholas J., & Gochanour, Eric, & Hamed, Ahmed, & Ibrahim, Mariam, & Barakat, Mohamed, & Mudireddy, Prashant R.. (March 2019).
Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis.
,
(),
-
. Retrieved from
http://hdl.handle.net/10342/8213
MLA:
Abdelfatah, Mohamed M., and Koutlas, Nicholas J., and Gochanour, Eric, and Hamed, Ahmed, and Ibrahim, Mariam, and Barakat, Mohamed, and Mudireddy, Prashant R..
"Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis". .
. (),
March 2019.
December 01, 2023.
http://hdl.handle.net/10342/8213.
Chicago:
Abdelfatah, Mohamed M. and Koutlas, Nicholas J. and Gochanour, Eric and Hamed, Ahmed and Ibrahim, Mariam and Barakat, Mohamed and Mudireddy, Prashant R.,
"Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis," , no.
(March 2019),
http://hdl.handle.net/10342/8213 (accessed
December 01, 2023).
AMA:
Abdelfatah, Mohamed M., Koutlas, Nicholas J., Gochanour, Eric, Hamed, Ahmed, Ibrahim, Mariam, Barakat, Mohamed, Mudireddy, Prashant R..
Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis. .
March 2019;
():
.
http://hdl.handle.net/10342/8213. Accessed
December 01, 2023.
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