Measurement of Oral Epithelial Thickness by Optical Coherence Tomography
Stasio, Dario Di; Lauritano, Dorina; Iquebal, Hasan; Romano, Antonio; Gentile, Enrica; Lucchese, Alberta
Optical coherence tomography (OCT) is a real-time, in-situ, non-invasive imaging device that is able to perform a cross-sectional evaluation of tissue microstructure based on the specific intensity of back-scattered and reflected light. The aim of the present study was to define normal values of epithelial thickness within the oral cavity. OCT measurements of epithelial thickness were performed in 28 healthy patients at six different locations within the oral cavity. Image analysis was performed using Image J 1.52 software. The healthy epithelium has a mean thickness of 335.59 ± 150.73 µm. According to its location within the oral cavity, the epithelium showed highest values in the region of the buccal mucosa (659.79 µm) and the thinnest one was observed in the mouth’s floor (100.07 µm). OCT has been shown to be useful for the evaluation of oral mucosa in vivo and in real time. Our study provides reference values for the epithelial thickness of multiple sites within the oral cavity. Knowledge of the thickness values of healthy mucosa is, therefore, of fundamental importance.
Stasio, Dario Di, & Lauritano, Dorina, & Iquebal, Hasan, & Romano, Antonio, & Gentile, Enrica, & Lucchese, Alberta. (August 2019). Measurement of Oral Epithelial Thickness by Optical Coherence Tomography. Diagnostics, (9:90), p.. Retrieved from http://hdl.handle.net/10342/8225
Stasio, Dario Di, and Lauritano, Dorina, and Iquebal, Hasan, and Romano, Antonio, and Gentile, Enrica, and Lucchese, Alberta. "Measurement of Oral Epithelial Thickness by Optical Coherence Tomography". Diagnostics. 9:90. (.), August 2019. October 25, 2020. http://hdl.handle.net/10342/8225.
Stasio, Dario Di and Lauritano, Dorina and Iquebal, Hasan and Romano, Antonio and Gentile, Enrica and Lucchese, Alberta, "Measurement of Oral Epithelial Thickness by Optical Coherence Tomography," Diagnostics 9, no. 90 (August 2019), http://hdl.handle.net/10342/8225 (accessed October 25, 2020).
Stasio, Dario Di, Lauritano, Dorina, Iquebal, Hasan, Romano, Antonio, Gentile, Enrica, Lucchese, Alberta. Measurement of Oral Epithelial Thickness by Optical Coherence Tomography. Diagnostics. August 2019; 9(90) . http://hdl.handle.net/10342/8225. Accessed October 25, 2020.