Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial

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Author
Goharani, Reza; Vahedian-Azimi, Amir; Farzanegan, Behrooz; Bashar, Farshid R.; Hajiesmaeili, Mohammadreza; Shojae, Seyedpouzhia; Madani, Seyed J.; Gohari-Moghaddam, Keivan; Hatamian, Sevak; Mosavinasab, Seyed M. M.; Khoshfetrat, Masoum; Khatir, Mohammad A. Khabiri; Miller, Andrew C.
Abstract
Objective: To determine if real-time compression feedback using a non-automated hand-held device improves patient outcomes from in-hospital cardiac arrest (IHCA). Methods: We conducted a prospective, randomized, controlled, parallel study (no crossover) of patients with IHCA in the mixed medical–surgical intensive care units (ICUs) of eight academic hospitals. Patients received either standard manual chest compressions or compressions performed with real-time feedback using the Cardio First Angel™ (CFA) device. The primary outcome was sustained return of spontaneous circulation (ROSC), and secondary outcomes were survival to ICU and hospital discharge. Results: One thousand four hundred fifty-four subjects were randomized; 900 were included. Sustained ROSC was significantly improved in the CFA group (66.7% vs. 42.4%, P < 0.001), as was survival to ICU discharge (59.8% vs. 33.6%) and survival to hospital discharge (54% vs. 28.4%, P < 0.001). Outcomes were not affected by intra-group comparisons based on intubation status. ROSC, survival to ICU, and hospital discharge were noted to be improved in inter-group comparisons of non-intubated patients, but not intubated ones. Conclusion: Use of the CFA compression feedback device improved event survival and survival to ICU and hospital discharge.
URI
http://hdl.handle.net/10342/8283
Subject
CPR, Resuscitation, Chest compression, Cardio First Angel™, Critical care, Intensive care
Date
2019-01-03
Citation:
APA:
Goharani, Reza, & Vahedian-Azimi, Amir, & Farzanegan, Behrooz, & Bashar, Farshid R., & Hajiesmaeili, Mohammadreza, & Shojae, Seyedpouzhia, & Madani, Seyed J., & Gohari-Moghaddam, Keivan, & Hatamian, Sevak, & Mosavinasab, Seyed M. M., & Khoshfetrat, Masoum, & Khatir, Mohammad A. Khabiri, & Miller, Andrew C.. (January 2019). Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial. Journal of Intensive Care, (7:5), p.. Retrieved from http://hdl.handle.net/10342/8283

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MLA:
Goharani, Reza, and Vahedian-Azimi, Amir, and Farzanegan, Behrooz, and Bashar, Farshid R., and Hajiesmaeili, Mohammadreza, and Shojae, Seyedpouzhia, and Madani, Seyed J., and Gohari-Moghaddam, Keivan, and Hatamian, Sevak, and Mosavinasab, Seyed M. M., and Khoshfetrat, Masoum, and Khatir, Mohammad A. Khabiri, and Miller, Andrew C.. "Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial". Journal of Intensive Care. 7:5. (.), January 2019. March 06, 2021. http://hdl.handle.net/10342/8283.
Chicago:
Goharani, Reza and Vahedian-Azimi, Amir and Farzanegan, Behrooz and Bashar, Farshid R. and Hajiesmaeili, Mohammadreza and Shojae, Seyedpouzhia and Madani, Seyed J. and Gohari-Moghaddam, Keivan and Hatamian, Sevak and Mosavinasab, Seyed M. M. and Khoshfetrat, Masoum and Khatir, Mohammad A. Khabiri and Miller, Andrew C., "Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial," Journal of Intensive Care 7, no. 5 (January 2019), http://hdl.handle.net/10342/8283 (accessed March 06, 2021).
AMA:
Goharani, Reza, Vahedian-Azimi, Amir, Farzanegan, Behrooz, Bashar, Farshid R., Hajiesmaeili, Mohammadreza, Shojae, Seyedpouzhia, Madani, Seyed J., Gohari-Moghaddam, Keivan, Hatamian, Sevak, Mosavinasab, Seyed M. M., Khoshfetrat, Masoum, Khatir, Mohammad A. Khabiri, Miller, Andrew C.. Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial. Journal of Intensive Care. January 2019; 7(5) . http://hdl.handle.net/10342/8283. Accessed March 06, 2021.
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