Refractory Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Treated With IVIg, Steroids, and a Combination of Anticoagulants: A Case Report
Author
Gonzales, Mia; Pipalia, Amrish; Weil, Andrew
Abstract
Heparin-induced thrombocytopenia (HIT) type II is caused by antibody production that bind complexes between heparin
and platelet factor 4 leading to platelet consumption and thrombosis. In a small subset of cases referred to as autoimmune
HIT, the antibodies activate platelets even in the absence of heparin. Refractory HIT is a type of autoimmune HIT in which
thrombocytopenia persists for weeks after heparin discontinuation and carries increased risk for thrombosis and more
severe thrombocytopenia. We present a case of refractory HIT with cerebral venous sinus thrombosis (CVST) that was
successfully treated with a change in anticoagulant alongside steroids and a second trial of intravenous immunoglobulin
(IVIg).
Date
2019-04-02
Citation:
APA:
Gonzales, Mia, & Pipalia, Amrish, & Weil, Andrew. (April 2019).
Refractory Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Treated With IVIg, Steroids, and a Combination of Anticoagulants: A Case Report.
,
(),
-
. Retrieved from
http://hdl.handle.net/10342/8296
MLA:
Gonzales, Mia, and Pipalia, Amrish, and Weil, Andrew.
"Refractory Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Treated With IVIg, Steroids, and a Combination of Anticoagulants: A Case Report". .
. (),
April 2019.
October 03, 2023.
http://hdl.handle.net/10342/8296.
Chicago:
Gonzales, Mia and Pipalia, Amrish and Weil, Andrew,
"Refractory Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Treated With IVIg, Steroids, and a Combination of Anticoagulants: A Case Report," , no.
(April 2019),
http://hdl.handle.net/10342/8296 (accessed
October 03, 2023).
AMA:
Gonzales, Mia, Pipalia, Amrish, Weil, Andrew.
Refractory Heparin-Induced Thrombocytopenia With Cerebral Venous Sinus Thrombosis Treated With IVIg, Steroids, and a Combination of Anticoagulants: A Case Report. .
April 2019;
():
.
http://hdl.handle.net/10342/8296. Accessed
October 03, 2023.
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