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    The potential role of magnetic resonance spectroscopy in image-guided radiotherapy

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    Author
    Nguyen, Mai Lin; Willows, Brooke; Khan, Rihan; Chi, Alexander; Kim, Lyndon; Nour, Sherif G.; Sroka, Thomas; Kerr, Christine; Godinez, Juan; Mills, Melissa; Karlsson, Ulf; Altdorfer, Gabor; Nguyen, Nam Phong; Jendrasiak, Gordon; The International Geriatric Radiotherapy Group
    Abstract
    Magnetic resonance spectroscopy (MRS) is a non-invasive technique to detect metabolites within the normal and tumoral tissues. The ability of MRS to diagnose areas of high metabolic activity linked to tumor cell proliferation is particularly useful for radiotherapy treatment planning because of better gross tumor volume (GTV) delineation. The GTV may be targeted with higher radiation dose, potentially improving local control without excessive irradiation to the normal adjacent tissues. Prostate cancer and glioblastoma multiforme (GBM) are two tumor models that are associated with a heterogeneous tumor distribution. Preliminary studies suggest that the integration of MRS into radiotherapy planning for these tumors is feasible and safe. Image-guided radiotherapy (IGRT) by virtue of daily tumor imaging and steep dose gradient may allow for tumor dose escalation with the simultaneous integrated boost technique (SIB) and potentially decrease the complications rates in patients with GBM and prostate cancers.
    URI
    http://hdl.handle.net/10342/8302
    Date
    2014-05-04
    Citation:
    APA:
    Nguyen, Mai Lin, & Willows, Brooke, & Khan, Rihan, & Chi, Alexander, & Kim, Lyndon, & Nour, Sherif G., & Sroka, Thomas, & Kerr, Christine, & Godinez, Juan, & Mills, Melissa, & Karlsson, Ulf, & Altdorfer, Gabor, & Nguyen, Nam Phong, & Jendrasiak, Gordon, & The International Geriatric Radiotherapy Group. (May 2014). The potential role of magnetic resonance spectroscopy in image-guided radiotherapy. , (), - . Retrieved from http://hdl.handle.net/10342/8302

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    MLA:
    Nguyen, Mai Lin, and Willows, Brooke, and Khan, Rihan, and Chi, Alexander, and Kim, Lyndon, and Nour, Sherif G., and Sroka, Thomas, and Kerr, Christine, and Godinez, Juan, and Mills, Melissa, and Karlsson, Ulf, and Altdorfer, Gabor, and Nguyen, Nam Phong, and Jendrasiak, Gordon, and The International Geriatric Radiotherapy Group. "The potential role of magnetic resonance spectroscopy in image-guided radiotherapy". . . (), May 2014. October 01, 2023. http://hdl.handle.net/10342/8302.
    Chicago:
    Nguyen, Mai Lin and Willows, Brooke and Khan, Rihan and Chi, Alexander and Kim, Lyndon and Nour, Sherif G. and Sroka, Thomas and Kerr, Christine and Godinez, Juan and Mills, Melissa and Karlsson, Ulf and Altdorfer, Gabor and Nguyen, Nam Phong and Jendrasiak, Gordon and The International Geriatric Radiotherapy Group, "The potential role of magnetic resonance spectroscopy in image-guided radiotherapy," , no. (May 2014), http://hdl.handle.net/10342/8302 (accessed October 01, 2023).
    AMA:
    Nguyen, Mai Lin, Willows, Brooke, Khan, Rihan, Chi, Alexander, Kim, Lyndon, Nour, Sherif G., Sroka, Thomas, Kerr, Christine, Godinez, Juan, Mills, Melissa, Karlsson, Ulf, Altdorfer, Gabor, Nguyen, Nam Phong, Jendrasiak, Gordon, The International Geriatric Radiotherapy Group. The potential role of magnetic resonance spectroscopy in image-guided radiotherapy. . May 2014; (): . http://hdl.handle.net/10342/8302. Accessed October 01, 2023.
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