| Author | Johnson, Jordan M. | |
| Author | Verkerke, Anthony R.P. | |
| Author | Maschek, J. Alan | |
| Author | Ferrara, Patrick J. | |
| Author | Lin, Chien-Te | |
| Author | Kew, Kimberly A. | |
| Author | Neufer, P. Darrell | |
| Author | Lodhi, Irfan J. | |
| Author | Cox, James E. | |
| Author | Funai, Katsuhiko | |
| Date Accessioned | 2020-04-21T18:44:09Z | |
| Date Available | 2020-04-21T18:44:09Z | |
| Date of Issue | 2019-11-08 | |
| Identifier (URI) | http://hdl.handle.net/10342/8309 | |
| Description | Phosphatidylethanolamine methyltransferase (PEMT) generates phosphatidylcholine (PC), the most abundant phospholipid in the mitochondria and an important acyl chain donor for cardiolipin (CL) biosynthesis. Mice lacking PEMT (PEMTKO) are cold-intolerant when fed a high-fat diet (HFD) due to unclear mechanisms. The purpose of this study was to determine whether PEMT-derived phospholipids are important for the function of uncoupling protein 1 (UCP1) and thus for maintenance of core temperature. | en_US |
| Title | Alternative splicing of UCP1 by non-cell-autonomous action of PEMT | en_US |
| Type | Article | en_US |
| Identifier (DOI) | 10.1016/j.molmet.2019.10.007 | |
| Journal Name | Alternative splicing of UCP1 by non-cell-autonomous action of PEMT | en_US |
| Journal Volume | 31 | en_US |
| Article Pages | 55-66 | en_US |
