Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy
Author
Chae-Kim, Jennifer J.; Waggener, K.; Gavrilova-Jordan, L.
Abstract
Embryo fragmentation, or extrusion of cell fragments, is a naturally occurring phenomenon that may be associated with impaired embryo development, failed implantation and decreased pregnancy rates. Previous studies have shown improvement in clinical outcomes after microsurgery to aspirate these cell fragments from embryos early during the embryo cleavage process. This case series of three patients with infertility showcases the successful application of the defragmentation technique in blastocyst stage embryos after in-vitro fertilization. The timing of defragmentation allows for better identification of those growth-arrested embryos that would benefit from “rescue” defragmentation. All three embryos demonstrated continued expansion and development after defragmentation, and resulted in clinical pregnancies.
Date
2020-10-19
Citation:
APA:
Chae-Kim, Jennifer J., & Waggener, K., & Gavrilova-Jordan, L.. (October 2020).
Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy.
,
(),
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Kim, J., Waggener, K., & Gavrilova-Jordan, L. (2020). Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy. Clinical Obstetrics, Gynecology and Reproductive Medicine, 6(6) https://doi.org/10.15761/COGRM.1000317. Retrieved from
http://hdl.handle.net/10342/9399
MLA:
Chae-Kim, Jennifer J., and Waggener, K., and Gavrilova-Jordan, L..
"Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy". .
. (),
October 2020.
September 30, 2023.
http://hdl.handle.net/10342/9399.
Chicago:
Chae-Kim, Jennifer J. and Waggener, K. and Gavrilova-Jordan, L.,
"Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy," , no.
(October 2020),
http://hdl.handle.net/10342/9399 (accessed
September 30, 2023).
AMA:
Chae-Kim, Jennifer J., Waggener, K., Gavrilova-Jordan, L..
Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy. .
October 2020;
():
.
http://hdl.handle.net/10342/9399. Accessed
September 30, 2023.
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