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    Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy

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    Author
    Chae-Kim, J.; Waggener, K.; Gavrilova-Jordan, L.
    Abstract
    Embryo fragmentation, or extrusion of cell fragments, is a naturally occurring phenomenon that may be associated with impaired embryo development, failed implantation and decreased pregnancy rates. Previous studies have shown improvement in clinical outcomes after microsurgery to aspirate these cell fragments from embryos early during the embryo cleavage process. This case series of three patients with infertility showcases the successful application of the defragmentation technique in blastocyst stage embryos after in-vitro fertilization. The timing of defragmentation allows for better identification of those growth-arrested embryos that would benefit from “rescue” defragmentation. All three embryos demonstrated continued expansion and development after defragmentation, and resulted in clinical pregnancies.
    URI
    http://hdl.handle.net/10342/9399
    Subject
     defragmentation; in-vitro fertilization; blastocyst; microsurgery; infertility 
    Date
    2020-10-19
    Citation:
    APA:
    Chae-Kim, J., & Waggener, K., & Gavrilova-Jordan, L.. (October 2020). Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy. Clinical Obstetrics, Gynecology and Reproductive Medicine, (6:6), p.. Retrieved from http://hdl.handle.net/10342/9399

    Display/Hide MLA, Chicago and APA citation formats.

    MLA:
    Chae-Kim, J., and Waggener, K., and Gavrilova-Jordan, L.. "Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy". Clinical Obstetrics, Gynecology and Reproductive Medicine. 6:6. (.), October 2020. August 12, 2022. http://hdl.handle.net/10342/9399.
    Chicago:
    Chae-Kim, J. and Waggener, K. and Gavrilova-Jordan, L., "Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy," Clinical Obstetrics, Gynecology and Reproductive Medicine 6, no. 6 (October 2020), http://hdl.handle.net/10342/9399 (accessed August 12, 2022).
    AMA:
    Chae-Kim, J., Waggener, K., Gavrilova-Jordan, L.. Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy. Clinical Obstetrics, Gynecology and Reproductive Medicine. October 2020; 6(6) . http://hdl.handle.net/10342/9399. Accessed August 12, 2022.
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