Browsing ObGyn by Author "Homesley, Howard D."
-
Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response
Salom, Emery; Penalver, Manuel; Homesley, Howard D.; Burrell, Matthew; Garrett, Audrey; Presant, Cary A.; Rutledge, James; Chernick, Michael; Hallquist, Allan; Perree, Mathieu (2012)Background This study was performed to determine if a chemotherapy-induced apoptosis assay (MiCK) could predict the best therapy for patients with ovarian cancer. Methods A prospective, multi-institutional and blinded ... -
Endometrial carcinoma in vitro chemosensitivity testing of single and combination chemotherapy regimens using the novel microculture kinetic apoptosis assay: implications for endometrial cancer treatment
Ballard, Karen S.; Homesley, Howard D.; Hodson, Charles; Presant, Cary A.; Rutledge, James; Hallquist, Allan; Perree, Mathieu (East Carolina University, 2010-03)Objective: The in vitro microculture kinetic (MiCK) apoptosis assay has been used to predict single or combination chemotherapy response in leukemia patients. This feasibility study addressed MiCK in endometrial cancer ... -
Present status and future direction of clinical trials in advanced endometrial carcinoma
Homesley, Howard D. (East Carolina University, 2008-09)Endometrial adenocarcinoma is staged surgically, and advanced endometrial carcinoma is considered to be FIGO stage III and IV. The Gynecologic Oncology Group (GOG) has come a long way in developing new strategies in the ...