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Endometrial carcinoma in vitro chemosensitivity testing of single and combination chemotherapy regimens using the novel microculture kinetic apoptosis assay: implications for endometrial cancer treatment
(East Carolina University, 2010-03)
Objective: The in vitro microculture kinetic (MiCK) apoptosis assay has been used to predict single or combination chemotherapy response in leukemia patients. This feasibility study addressed MiCK in endometrial cancer ...
Present status and future direction of clinical trials in advanced endometrial carcinoma
(East Carolina University, 2008-09)
Endometrial adenocarcinoma is staged surgically, and advanced endometrial carcinoma is considered to be FIGO stage III and IV. The Gynecologic Oncology Group (GOG) has come a long way in developing new strategies in the ...
Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
(2003-07-22)
The present application describes a monoclonal antibody selected from the group consisting of monoclonal antibody DS6, monoclonal antibodies that specifically bind to the antigen or epitope bound by monoclonal antibody ...
Gestational Diabetes Is Characterized by Reduced Mitochondrial Protein Expression and Altered Calcium Signaling Proteins in Skeletal Muscle
(2014)
The rising prevalence of gestational diabetes mellitus (GDM) affects up to 18% of pregnant women with immediate and long-term metabolic consequences for both mother and infant. Abnormal glucose uptake and lipid oxidation ...
Surgical Management of Massive Labial Edema in a Gravid Preeclamptic Diabetic
(2014)
Background. Massive labial edema is a rare complication during pregnancy that can jeopardize vaginal delivery, as well as leading to maternal and fetal morbidity. It can be related to systemic pathologies, but has been ...
Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response
(2012)
Background
This study was performed to determine if a chemotherapy-induced apoptosis assay (MiCK) could predict the best therapy for patients with ovarian cancer.
Methods
A prospective, multi-institutional and blinded ...
Postpartum Prolapsed Leiomyoma with Uterine Inversion Managed by Vaginal Hysterectomy
(2014)
Background. Uterine inversion is a rare, but life threatening, obstetrical emergency which occurs when the uterine fundus collapses into the endometrial cavity. Various conservative and surgical therapies have been outlined ...