Browsing Oncology by Author "Justus, Calvin R."
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Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
Justus, Calvin R.; Dong, Lixue; Yang, Li V. (2013-10)The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ...