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The Actin Binding Protein, Fesselin, is a Member of the Synaptopodin Family

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dc.contributor.authorSchroeter, Mechthild M.en_US
dc.contributor.authorBeall, Brenten_US
dc.contributor.authorHeid, Hans W.en_US
dc.contributor.authorChalovich, Josephen_US
dc.date.accessioned2011-01-21T21:22:12Zen_US
dc.date.accessioned2011-05-17T01:27:00Z
dc.date.available2011-01-21T21:22:12Zen_US
dc.date.available2011-05-17T01:27:00Z
dc.date.issued2008-07en_US
dc.description.abstractFesselin is a natively unfolded protein that is abundant in avian smooth muscle. Like many natively unfolded proteins, fesselin has multiple binding partners including actin, myosin, calmodulin and α-actinin. Fesselin accelerates actin polymerization and bundles actin. These and other observations suggest that fesselin is a component of the cytoskeleton. We have now cloned fesselin and have determined the cDNA derived amino acid sequence. We verified parts of the sequence by Edman analysis and by mass spectroscopy. Our results confirmed fesselin is homologous to human synaptopodin 2 and belongs to the synaptopodin family of proteins. Originally published Biochem Biophys Res Commun. Vol. 371, No. 3, July 2008en_US
dc.identifier.citationBiochemical and Biophysical Research Communications; 371:3 p. 582-586en_US
dc.identifier.doi10.1016/j.bbrc.2008.04.134
dc.identifier.pmidPMC2453309en_US
dc.identifier.urihttp://hdl.handle.net/10342/3089en_US
dc.language.isoen_USen_US
dc.publisherEast Carolina Universityen_US
dc.relation.urihttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WBK-4SF9H68-C&_user=634873&_coverDate=07%2F04%2F2008&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000033758&_version=1&_urlVersion=0&_userid=634873&md5=d972c319b29cb0cce3ad1aa4a8fd6d39&searchtype=aen_US
dc.subjectFesselinen_US
dc.subjectSynaptopodinen_US
dc.subjectMyopodinen_US
dc.subjectActin binding proteinen_US
dc.subjectActin polymerizationen_US
dc.subjectCa-calmodulin regulationen_US
dc.titleThe Actin Binding Protein, Fesselin, is a Member of the Synaptopodin Familyen_US
dc.typeArticleen_US
ecu.journal.issue3
ecu.journal.nameBiochemical and Biophysical Research Communications
ecu.journal.pages582-586
ecu.journal.volume371

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