Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase

Abstract

A composition, device, kit and method for countering or diagnosing cytidine deaminase or deoxycytidine deaminase over-expression or a disorder associated with it, or an increase in number or toxicity of pro-inflammatory cells that over-express cytidine deaminase or deoxycytidine deaminase or a disorder associated with it, utilizing an agent of the formula C.sub.7 N.sub.3 H.sub.8 O.sub.2 R.sup.1 R.sup.2 XX.sup.1, wherein X and X.sup.1 are each independently C or N, R.sup.1 is lower alkyl, alkenyl and alkynyl, halogen or haloalkyl, and R.sup.2 is H, --N.sub.3 --OH, amino or halogen; or pharmaceutically acceptable salts thereof.