Agent and method for treating disorders associated with cytidine deaminase or deoxycytidine deaminase overexpression
dc.contributor.author | Nyce, Jonathan W. | |
dc.date.accessioned | 2016-02-05T17:01:21Z | |
dc.date.available | 2016-02-05T17:01:21Z | |
dc.date.issued | 2000-10-24 | |
dc.description.abstract | An agent of the chemical formula C.sub.7 N.sub.3 H.sub.8 O.sub.2 R.sup.1 R.sup.2 XX.sup.1, wherein X and X.sup.1 are each independently C or N but not simultaneously, R.sup.1 is lower alkyl, alkenyl or alkynyl, halogen or haloalkyl, and R.sup.2 is H, --N.sub.3 --OH, amino or halogen; or pharmaceutically acceptable salts thereof. A method of treating a disorder associated with the overexpression of cytidine deaminase or deoxycytidine deaminase comprises administering to a subject in need of the treatment a compound of the chemical formula ##STR1## wherein X and X.sub.1 are each independently C or N; R.sup.1 is lower alkyl, lower alkenyl, lower alkynyl, halogen, or haloalkyl; and R.sup.2 H, --N.sub.3, --OH, amino, or halogen; or a pharmaceutically acceptable salt thereof in an amount effective to treat the disorder. Pharmaceutical formulations useful in the method of the present invention are also disclosed. | en_US |
dc.identifier.other | U.S. Patent No. 6,136,791 | |
dc.identifier.uri | http://hdl.handle.net/10342/5175 | |
dc.title | Agent and method for treating disorders associated with cytidine deaminase or deoxycytidine deaminase overexpression | en_US |
dc.type | Patent | en_US |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- Nyce3.pdf
- Size:
- 1.94 MB
- Format:
- Adobe Portable Document Format
- Description:
- Nyce 3