Long-Term Mortality of 306,868 Patients with Multi-Vessel Coronary Artery Disease: CABG versus PCI

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dc.contributor.authorEfird, Jimmy T.
dc.contributor.authorO'Neal, Wesley T.
dc.contributor.authorDavies, Stephen W.
dc.contributor.authorKennedy, Whitney L.
dc.contributor.authorAlger, Lada N.
dc.contributor.authorO'Neal, Jason B.
dc.contributor.authorFerguson, T. Bruce
dc.contributor.authorKypson, Alan P.
dc.date.accessioned2016-07-28T18:02:32Z
dc.date.available2016-07-28T18:02:32Z
dc.date.issued2013-08
dc.description.abstractBackground Several randomized controlled trials (RCT) have reported no difference in long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). The purpose of this pooled observational analysis was to compare recent retrospective studies examining long-term survival of patients with multi-vessel coronary artery disease undergoing CABG and PCI. Methodology We searched Medline for observational studies comparing long-term (>1 year) survival between CABG and PCI for the treatment of multi-vessel coronary artery disease over the past 10 years. Results Eight studies met inclusion criteria. A total of 306,868 patients (155,502 CABG; 151,366 PCI) were identified. Follow-up ranged from 1 to 8 years. Mantel-Haenszel combined hazard ratios (HR) for mortality demonstrated a protective benefit of CABG compared with PCI (HR=0.77, 95%CI=0.75–0.79). Conclusion These findings suggest a long-term survival advantage for CABG compared with PCI in patients with multi-vessel coronary artery disease.en_US
dc.identifier.citationBritish journal of medicine and medical research; 3:4 p. 1248-1257en_US
dc.identifier.issn2231-0614
dc.identifier.pmidpmc3942885en_US
dc.identifier.urihttp://hdl.handle.net/10342/5850
dc.relation.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942885/en_US
dc.subjectCABGen_US
dc.subjectPCIen_US
dc.subjectsurvivalen_US
dc.subjectlong-termen_US
dc.titleLong-Term Mortality of 306,868 Patients with Multi-Vessel Coronary Artery Disease: CABG versus PCIen_US
dc.typeArticleen_US
ecu.journal.issue4en_US
ecu.journal.nameBritish journal of medicine and medical researchen_US
ecu.journal.pages1248-1257en_US
ecu.journal.volume3en_US

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