Variation in pigmentation gene expression is associated with distinct aposematic color morphs in the poison frog Dendrobates auratus

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dc.contributor.authorStuckert, Adam M. M.
dc.contributor.authorMoore, Emily
dc.contributor.authorCoyle, Kaitlin P.
dc.contributor.authorDavison, Ian
dc.contributor.authorMacManes, Matthew D.
dc.contributor.authorRoberts, Reade
dc.contributor.authorSummers, Kyle
dc.contributor.departmentBiology
dc.date.accessioned2019-04-30T18:26:03Z
dc.date.available2019-04-30T18:26:03Z
dc.date.issued2019-04-18
dc.date.updated2019-04-21T03:18:47Z
dc.description.abstractAbstract Background Color and pattern phenotypes have clear implications for survival and reproduction in many species. However, the mechanisms that produce this coloration are still poorly characterized, especially at the genomic level. Here we have taken a transcriptomics-based approach to elucidate the underlying genetic mechanisms affecting color and pattern in a highly polytypic poison frog. We sequenced RNA from the skin from four different color morphs during the final stage of metamorphosis and assembled a de novo transcriptome. We then investigated differential gene expression, with an emphasis on examining candidate color genes from other taxa. Results Overall, we found differential expression of a suite of genes that control melanogenesis, melanocyte differentiation, and melanocyte proliferation (e.g., tyrp1, lef1, leo1, and mitf) as well as several differentially expressed genes involved in purine synthesis and iridophore development (e.g., arfgap1, arfgap2, airc, and gart). Conclusions Our results provide evidence that several gene networks known to affect color and pattern in vertebrates play a role in color and pattern variation in this species of poison frog.
dc.identifier.citationBMC Evolutionary Biology. 2019 Apr 18;19(1):85
dc.identifier.doihttps://doi.org/10.1186/s12862-019-1410-7
dc.identifier.urihttp://hdl.handle.net/10342/7164
dc.language.rfc3066en
dc.rights.holderThe Author(s).
dc.titleVariation in pigmentation gene expression is associated with distinct aposematic color morphs in the poison frog Dendrobates auratus
dc.typeArticleen_US

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